The genomic legacy of selectively breeding rhesus macaques for HIV/AIDS-related research
Martha M. Lyke, A Bagwell, D Newman, S Galindo, T Church, C Christensen, SB Gray, Laura A. Cox, CN Ross, Deepak Kaushal, Ian H. Cheeseman, Shelley A. Cole
The paper shows that targeted breeding strategies in rhesus macaques reduced SIV-refractory MHC haplotypes without decreasing genetic diversity.
bioRxiv · May 26, 2025 · PreprintGenomics