CRISPR Turbo Accelerated Knock Out (CRISPy TAKO) for rapid in vivo screening of gene function
Sonja Lorean Plasil, A Seth, Gregg E. Homanics
This paper introduces CRISPy TAKO, a CRISPR/Cas9 method to generate homozygous knockout mice in one generation, validated using MyD88-/- mice showing expected ethanol-related behavioral changes.
Frontiers in Genome Editing · Oct 21, 2020Peer-reviewedGenetics