Single-nucleus RNA-seq identifies Huntington disease astrocyte states
Osama Al‐Dalahmah, Alexander A. Sosunov, A Shaik, Kenneth Ofori, Yang Liu, Jean Paul Vonsattel, István Adorján, Vilas Menon, James E. Goldman
This study uses snRNA-seq to identify distinct transcriptional states of astrocytes in Huntington disease, revealing gene expression changes compared to controls.
Acta Neuropathologica Communications · Feb 18, 2020Peer-reviewedNeuroscience