Intestinal helminth skews DC2 development towards regulatory phenotype to counter the anti-helminth immune response.
Anna T. Andrusaite, Olivia J. Ridgewell, A. A. Ahlback, Holly C. Webster, Hiroki Yamaguchi, Molly Peel, Annika Frede, Sarwah Al-Khalidi, Andrew Farthing, Anna L. L. Heawood, Annabelle Smith, Edward Roberts, Allan McI. Mowat, R. M. M. Maizels, Georgia Perona‐Wright, Simon W. F. Milling
This study shows that intestinal helminth infection shifts DC2 development towards a regulatory phenotype to suppress anti-helminth immunity.
bioRxiv · Sep 11, 2024 · PreprintImmunology