Prolonged over-expression of PLK4 amplifies centrosomes through formation of inter-connected centrosome rosette clusters
S. C. Ozcan, B. M. Kalkan, E. Cicek, A. A. Canbaz, C. Acilan
This paper shows that prolonged PLK4 overexpression leads to centrosome amplification through interconnected centrosome rosette clusters (CRCs) that depend on centrosomal linker proteins.
bioRxiv · Oct 10, 2023 · PreprintCell Biology