Author

C. Acilan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. M. Kalkan· 2 shared E. Cicek· 2 shared M. Gonen· 2 shared S. C. Ozcan· 2 shared A. A. Canbaz· 1 shared A. C. Aksu· 1 shared A. Cingoz· 1 shared A. P. Cribbs· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

B. M. Kalkan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Less is More: Nek2A Unclusters Extra Centrosomes and Induces Cell Death in Cancer Cells via KIF2C Interaction

B. M. Kalkan, S. C. Ozcan, E. Cicek, M. Gonen, C. Acilan

This study shows Nek2A unclusters extra centrosomes and induces cell death in cancer cells, but not in normal cells, through interaction with KIF2C.

bioRxiv · Nov 21, 2023Cancer Biology

Prolonged over-expression of PLK4 amplifies centrosomes through formation of inter-connected centrosome rosette clusters

S. C. Ozcan, B. M. Kalkan, E. Cicek, A. A. Canbaz, C. Acilan

This paper shows that prolonged PLK4 overexpression leads to centrosome amplification through interconnected centrosome rosette clusters (CRCs) that depend on centrosomal linker proteins.

bioRxiv · Oct 10, 2023 · PreprintCell Biology

Epigenetic-focused CRISPR/Cas9 screen identifies ASH2L as a regulator of glioblastoma cell survival

E. Ozyerli-Goknar, E. Y. Kala, A. C. Aksu, I. Bulut, A. Cingoz, S. Nizamuddin, M. Biniossek, F. Seker-Polat, T. Morova, C. Aztekin, S. H. A. Kung, H. Syed, N. Tuncbag, M. Gonen, M. Philpott, , T. Bagci-Onder

This study uses CRISPR/Cas9 screens to identify ASH2L as a key regulator of glioblastoma cell survival, with downstream effects on cell cycle and apoptosis.

bioRxiv · Aug 17, 2022 · PreprintCancer Biology