Evidence for Deleterious Antigenic Imprinting in SARS-CoV-2 Immune Response
S. R. Sen, E. C. Sanders, A. M. Santos, K. Bhuvan, D. Y. Tang, A. A. Gelston, B. M. Miller, J. L. Ricks-Oddie, G. A. Weiss
This study identifies cross-reactive antibodies against SARS-CoV-2 Ep9 epitope that originated from prior influenza infection, suggesting antigenic imprinting contributes to severe COVID-19 outcomes.
bioRxiv · May 21, 2021 · PreprintImmunology