Biomechanical Regulation of Breast Cancer Metastasis and Progression
A. Spencer, A. Sligar, D. Chavarria, J. Lee, D. Choksi, N. Patil, H. Lee, A. Veith, W. Riley, S. Desai, A. Abbaspour, R. Singeetham, A. Baker
This study investigates how mechanical forces affect breast cancer cell behavior, finding that tension alters gene expression, increases chemoresistance, and promotes metastasis through specific signaling pathways.
bioRxiv · Jan 21, 2020Cancer Biology