A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice
L. Pernomian, E. W. Waigi, V. Nguyen, A. Mohammed, T. J. Costa, M. T. Fontes, J. L. Kubinak, A. Aitken, V. C. Biancardi, D. A. Sinclair, C. G. McCarthy, Y. Wang, W. Tan, C. F. Wenceslau
This study shows that reprogramming endothelial cells in hypertensive mice with OSK factors reduces blood pressure by inhibiting EndMT and vascular damage.
bioRxiv · May 20, 2024Physiology