Generation of novel diagnostic and therapeutic exosomes to detect and deplete pro-tumorigenic M2-macrophages.
M. H. Rashid, T. F. Borin, R. Ara, A. Alptekin, Y. Liu, A. S. Arbab
This study develops exosomes targeting M2-macrophages for detecting and depleting them, showing reduced tumor burden and improved survival in a breast cancer model.
bioRxiv · Nov 20, 2019 · PreprintCancer Biology