Author

T. F. Borin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. S. Arbab· 4 shared M. H. Rashid· 4 shared R. Ara· 4 shared Y. Liu· 3 shared B. R. Achyut· 2 shared K. Angara· 2 shared R. Piranlioglu· 2 shared A. Alptekin· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersCancer Biology

A. S. Arbab

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4 papers

Recent·Most cited

The critical immunosuppressive effect of MDSC-derived exosomes in the tumor microenvironment.

M. H. Rashid, T. F. Borin, R. Ara, R. Piranlioglu, B. R. Achyut, H. Korkaya, Y. Liu, A. S. Arbab

This study shows MDSC-derived exosomes suppress CD8 T-cells and promote tumor growth by modulating immunosuppression and inflammation in the tumor microenvironment.

Oncology Reports · Jan 14, 2021Peer-reviewedCancer Biology

Changes in the tumor microenvironment and treatment outcome in glioblastoma: A pilot study

S. Ali, T. F. Borin, R. Piranlioglu, R. Ara, I. Lebedyeva, K. Angara, B. R. Achyut, A. S. Arbab, M. H. Rashid

This study investigates changes in the tumor microenvironment (TME) in response to different therapies in a glioblastoma model, finding that TME-targeting therapies improve survival.

bioRxiv · Feb 3, 2020Cancer Biology

Generation of novel diagnostic and therapeutic exosomes to detect and deplete pro-tumorigenic M2-macrophages.

M. H. Rashid, T. F. Borin, R. Ara, A. Alptekin, Y. Liu, A. S. Arbab

This study develops exosomes targeting M2-macrophages for detecting and depleting them, showing reduced tumor burden and improved survival in a breast cancer model.

bioRxiv · Nov 20, 2019 · PreprintCancer Biology

Differential in vivo biodistribution of 131I-labeled exosomes from diverse cellular origins and its implication in the theranostic application.

M. H. Rashid, T. F. Borin, R. Ara, K. Angara, J. Cai, B. Achyut, Y. Liu, A. S. Arbab

The paper shows differential in vivo distribution of 131I-labeled exosomes from different cell sources and links this to their protein content, with implications for theranostic applications.

bioRxiv · Mar 3, 2019Cancer Biology