Allosteric feed-forward activation of AP-2 via FCHO- BMP2K axis promotes clathrin-mediated endocytosis
S. T. Ramesh, N. V. Kolaparamba, A. B. Ashok, N. Qathoon, S. Mohanty, R. K. Swain, U. K. Perunthottathu
The paper shows that FCHO activates AP-2 via BMP2K to promote clathrin-mediated endocytosis, with implications for CCP maturation and embryonic development.
bioRxiv · Dec 10, 2019 · PreprintCell Biology