S. Mohanty

Synergistic Hypoxia and Apoptosis Conditioning Unleashes Superior Mesenchymal Stem Cells Efficacy in Acute Graft-versus-Host-Disease

This study shows that hypoxia and apoptosis conditioning of WJ-MSCs enhances their immune regulatory capacity in aGVHD by promoting Treg differentiation and M2 macrophage polarization.

Dectin-1 Stimulation Promotes a Distinct Inflammatory Signature in the Setting of HIV-infection and Aging

This study shows that HIV-positive older adults have a unique inflammatory response to Dectin-1 stimulation, marked by increased cytokines and immune activation.

Case report on lethal dog attacks on adult rhesus macaques (Macaca mulatta) in an anthropogenic landscape

The paper reports three cases of dog attacks on rhesus macaques in Northern India, highlighting the impact of domesticated dogs on primate populations and predator-prey dynamics in anthropogenic landscapes.

Detergent induced structural perturbations in peanut agglutinin: Insights from spectroscopic and molecular dynamic simulation studies

This study investigates how SDS and CTAB detergents affect the structure of peanut agglutinin using spectroscopic and molecular dynamics simulations, revealing structural perturbations and conformational changes.

CMTM6 mediates cisplatin resistance in OSCC by regulating AKT/c-MYC driven ribosome biogenesis

This study identifies CMTM6 as a regulator of ribosome biogenesis in cisplatin-resistant OSCC, showing that targeting this pathway can restore chemosensitivity.

Platelet response to influenza vaccination reflects effects of aging

This study examines how aging and frailty affect platelet function before and after influenza vaccination, revealing age-related changes in activation and translation.

Chlorpyrifos degradation by combined solar photo-Fenton and bacterial metabolism and simultaneous toxicity analysis in zebrafish (Danio rerio)

This study evaluates the combined solar photo-Fenton and bacterial degradation of chlorpyrifos in wastewater and assesses its toxicity to zebrafish.

No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination

This study investigates whether COVID-19 mRNA vaccination affects pregnancy outcomes or induces anti-syncytin-1 antibodies, finding no evidence of fetal defects or increased antibody levels.

Reversible brain edema in experimental cerebral malaria is associated with transcellular blood-brain barrier disruption and delayed microhemorrhages

This study identifies transcellular blood-brain barrier disruption as a mechanism for reversible brain swelling in experimental cerebral malaria, with implications for therapeutic strategies.

CRISPR-based kinome-screening revealed MINK1 as a druggable player to rewire 5FU-resistance in OSCC through AKT/MDM2/p53 axis

The paper identifies MINK1 as a key driver of 5FU resistance in OSCC using CRISPR screening and shows that lestaurtinib can restore 5FU sensitivity.

The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-kB activation

This study identifies UBE4B as a host factor that ubiquitinates HTLV-1 Tax to promote NF-κB activation and cell survival in ATLL.

CMTM6 drives cisplatin resistance in OSCC by regulating AKT mediated Wnt signaling

This study identifies CMTM6 as a driver of cisplatin resistance in OSCC by activating AKT-mediated Wnt signaling, leading to increased survival gene expression and tumor growth.

RRBP1 rewires cisplatin resistance in Oral Squamous Cell Carcinoma by regulating YAP-1

This study identifies RRBP1 as a key regulator of cisplatin resistance in OSCC, showing its role in YAP-1 regulation and demonstrating that Radezolid can restore cisplatin sensitivity.

Allosteric feed-forward activation of AP-2 via FCHO- BMP2K axis promotes clathrin-mediated endocytosis

The paper shows that FCHO activates AP-2 via BMP2K to promote clathrin-mediated endocytosis, with implications for CCP maturation and embryonic development.

Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults

This study identifies shared and seasonal molecular signatures of influenza vaccination in young and older adults, revealing age-specific gene expression patterns linked to antibody responses.

Nano-enhanced optical gene delivery to retinal degenerated mice

This study introduces a laser-based nano-enhanced optical delivery method for gene delivery to retinal cells in mice, showing successful opsin expression in degenerated retinas.

Macrophage migration inhibitory factor (MIF) of Syrian golden hamster (Mesocricetus auratus) has similar structure and function as human MIF and promotes pancreatic tumor growth in vivo

This study characterizes the structure and function of Syrian golden hamster MIF, showing similarity to human MIF and demonstrating its role in promoting pancreatic tumor growth in vivo.

22-hydroxycholesterol leads to efficient dopaminergic specification of human Mesenchymal Stem Cells

This study shows that 22-hydroxycholesterol promotes dopaminergic neuron generation from human mesenchymal stem cells with higher efficiency than non-DA cells.