Author

A. B. Hehl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

C. Faso· 3 shared J. B. Dacks· 2 shared R. Santos· 2 shared S. V. Pipaliya· 2 shared A. Astvaldsson· 1 shared A. Bougdour· 1 shared A. Gruber· 1 shared A. Roger· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCell Biology

C. Faso

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

In vitro production of cat-restricted Toxoplasma pre-sexual stages by epigenetic reprogramming

A. V. Antunes, M. Shahinas, C. Swale, D. C. Farhat, C. Ramakrishnan, C. Bruley, D. Cannella, C. Corrao, Y. Coute, A. B. Hehl, A. Bougdour, I. Coppens, M.-a. Hakimi

This study shows that AP2XII-1 and AP2XI-2 transcription factors reprogram Toxoplasma gondii tachyzoites to merozoites in vitro, enabling the production of pre-sexual stages without using cats.

bioRxiv · Jan 16, 2023 · PreprintMicrobiology

Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Fornicata

R. Santos, A. Astvaldsson, S. V. Pipaliya, J. P. Zumthor, J. B. Dacks, S. Svard, A. B. Hehl, C. Faso

The paper characterizes endocytic compartments in Giardia lamblia using microscopy and phylogenetic analysis, revealing loss of clathrin light chain and emergence of a CLC analog in the Fornicata lineage.

bioRxiv · Apr 14, 2022 · PreprintCell Biology

Unexpected organellar locations of ESCRT machinery in Giardia intestinalis and complex evolutionary dynamics spanning the transition to parasitism in the lineage Fornicata

S. V. Pipaliya, R. Santos, D. Salas-Leiva, E. A. Balmer, C. D. Wirdnam, A. Roger, A. B. Hehl, C. Faso, J. B. Dacks

bioRxiv · Feb 11, 2021Evolutionary Biology

Phosphoinositide-binding proteins mark, shape and functionally modulate highly-diverged endocytic compartments in the parasitic protist Giardia lamblia

L. Cernikova, C. Faso, A. B. Hehl

This study identifies PIP-binding proteins involved in clathrin-mediated endocytosis in Giardia lamblia, revealing a divergent network compared to model systems.

PLOS Pathogens · Feb 24, 2020Peer-reviewedMicrobiology

Mitochondrial targeting of glycolysis in a major lineage of eukaryotes

C. Rio Bartulos, M. B. Rogers, T. A. Williams, E. Gentekaki, H. Brinkmann, R. Cerff, M.-F. Liaud, A. B. Hehl, N. R. Yarlett, A. Gruber, P. G. Kroth, M. van der Giezen

The paper identifies mitochondrial targeting signals for glycolytic enzymes in stramenopiles, revealing a novel metabolic pathway in these eukaryotes and suggesting new strategies for combating pathogens like Phytophthora infestans.

bioRxiv · Jan 31, 2018Evolutionary Biology