Constitutive high expression of NOXA sensitizes human embryonic stem cells for rapid cell death
R. Basundra, S. Kapoor, E. Hollville, N. Kiapour, A. B. Lopez, N. M. Melchiorre, M. Deshmukh
This study shows that high NOXA levels in hES cells antagonize MCL1, enabling rapid apoptosis in response to DNA damage.
bioRxiv · Jan 13, 2021Cell Biology