Innovative, rapid, high throughput method for drug repurposing in a pandemic - a case study of SARS-CoV-2 and COVID-19
S. O. Bello, A. Yunusa, A. A. Adamu, M. U. Imam, M. B. Bello, A. B. Shuaibu, E. U. Igumbor, Z. G. Habib, M. A. Popoola, C. L. Ochu, A. Y. Bello, Y. Y. Deeni, I. Okoye
This study identifies potential drugs for COVID-19 by combining computational and wet-lab methods, finding that erythromycin, pyridoxine, folic acid, and retapamulin inhibit SARS-CoV-2 induced cytopathic effect in Vero cells at clinically achievable concentrations.
bioRxiv · Dec 25, 2022Pharmacology & Toxicology