Erythromycin, Retapamulin, Pyridoxine, Folic acid, and Ivermectin dose-dependently inhibit cytopathic effect, Papain-like Protease, and MPRO of SARS-CoV-2
S. O. Bello, M. U. Imam, M. B. Bello, A. Yunusa, A. A. Adamu, A. Shuaibu, E. U. Igumbor, Z. G. Habib, M. A. Popoola, C. L. Ochu, A. Y. Bello, Y. Y. Deeni, I. Okoye
The paper shows that Erythromycin, Retapamulin, Pyridoxine, Folic acid, and Ivermectin inhibit SARS-CoV-2 cytopathic effect and proteases in a dose-dependent manner, with IC50 values within clinical concentrations for most drugs.
bioRxiv · Dec 28, 2022 · PreprintPharmacology & Toxicology