Engineering of human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia and solid tumor metastasis
A. Grigoryan, D. Zacharaki, A. Balhuizen, C. R. Come, A.-K. Frank, A. Garcia Garcia, K. Aaltonen, A. Manas, J. Esfandyari, N. Kalantari, P. Kjellman, S. Prithiviraj, E. Englund, C. D. Madsen, B. Porse, , P. E. Bourgine
This study develops standardized humanized mini-bones to model hematopoiesis, leukemia, and solid tumor metastasis by engrafting human blood and cancer samples.
bioRxiv · Sep 11, 2021Bioengineering