Author

P. E. Bourgine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Garcia Garcia· 2 shared D. Zacharaki· 2 shared S. Prithiviraj· 2 shared A. Balhuizen· 1 shared A. Grigoryan· 1 shared A. Manas· 1 shared A. Subramaniam· 1 shared A.-K. Frank· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioengineering

A. Garcia Garcia

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

S. Prithiviraj, A. Garcia Garcia, K. Linderfalk, B. Yiguang, S. Ferveur, L. N. Falck, A. Subramaniam, S. Mohlin, D. H. Gil, S. J. Dupard, D. Zacharaki, D. B. Raina, P. E. Bourgine

This study uses CRISPR/Cas9 to edit human mesenchymal stem cells to produce engineered extracellular matrices with modified VEGF and RUNX2 expression, showing altered osteogenic properties.

bioRxiv · Jul 28, 2023Bioengineering

Engineering of human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia and solid tumor metastasis

A. Grigoryan, D. Zacharaki, A. Balhuizen, C. R. Come, A.-K. Frank, A. Garcia Garcia, K. Aaltonen, A. Manas, J. Esfandyari, N. Kalantari, P. Kjellman, S. Prithiviraj, E. Englund, C. D. Madsen, B. Porse, , P. E. Bourgine

This study develops standardized humanized mini-bones to model hematopoiesis, leukemia, and solid tumor metastasis by engrafting human blood and cancer samples.

bioRxiv · Sep 11, 2021Bioengineering