The energy landscape reshaped by strain-specific mutations underlies the long-range epistasis in NS1 evolution of influenza A virus
I. Kim, A. Dubrow, B. Zuniga, B. Zhao, N. Sherer, A. Bastiray, P. Li, J.-H. Cho
The paper investigates how strain-specific mutations in the NS1 protein of influenza A virus reshape the energy landscape, leading to long-range epistasis.
bioRxiv · May 30, 2022 · PreprintBiophysics