Author

J.-H. Cho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Bastiray· 1 shared A. Davidoff· 1 shared A. Dubrow· 1 shared A. Murphy· 1 shared A. Polash· 1 shared B. Zhao· 1 shared B. Zuniga· 1 shared C. M. Jablonowski· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiophysics

A. Bastiray

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Homeostatic Dysregulation of Systemic CD8+ T Cell Compartment in Lung Cancer Patients

S.-W. Lee, J. S. Yun, Y. J. Kim, H.-O. Kim, H.-J. Cho, C.-K. Park, I.-J. Oh, J.-H. Cho

The paper shows cancer causes systemic CD8+ T cell homeostatic dysregulation, leading to uncontrolled differentiation and poor immune checkpoint inhibitor response.

bioRxiv · Dec 27, 2023 · PreprintImmunology

Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor

J. YANG, C. M. Jablonowski, W. Quarni, S. Singh, H. Tan, D. H. Bostanthirige, H. Jin, J. Fang, T.-C. Chang, D. Finkelstein, J.-H. Cho, D. Hu, V. Pagala, S. M. Sakurada, S. M. Pruett-Miller, , G. Wu

This study shows JMJD6 links pre-mRNA splicing and metabolism in MYC-driven cancers, and its inhibition enhances therapeutic response to splicing inhibitors.

bioRxiv · Jun 26, 2023Cancer Biology

Mature microRNA-binding protein QKI promotes microRNA-mediated gene silencing

J.-H. Yoon, K.-W. Min, M. H. Jo, M. Song, S. Ko, J. W. Lee, M. J. Shim, K. Kim, H. B. Park, S. Ha, H. Mun, A. Polash, M. Hafner, J.-H. Cho, D.-S. Kim, , S.-U. Kang

The paper identifies QKI as a novel microRNA-binding protein that enhances AGO2/let-7b-mediated gene silencing and suppresses tumor growth.

bioRxiv · Mar 15, 2023Biochemistry

The energy landscape reshaped by strain-specific mutations underlies the long-range epistasis in NS1 evolution of influenza A virus

I. Kim, A. Dubrow, B. Zuniga, B. Zhao, N. Sherer, A. Bastiray, P. Li, J.-H. Cho

The paper investigates how strain-specific mutations in the NS1 protein of influenza A virus reshape the energy landscape, leading to long-range epistasis.

bioRxiv · May 30, 2022 · PreprintBiophysics

Molecular mapping of qBK1Z, a major QTL for bakanae disease resistance in rice

S.-B. Lee, N. Kim, S. Jo, Y.-J. Hur, J.-H. Cho, J.-y. Lee, J.-H. Lee, Y.-C. Song, J.-M. Ko, Y.-S. Seo, J. Lee, M. Bombay, S.-R. Kim, D.-S. Park

This study identifies a major QTL, qBK1Z, for bakanae disease resistance in rice using QTL mapping in recombinant inbred lines derived from a resistant and susceptible variety.

bioRxiv · May 18, 2020Plant Biology