Hyperactive WNT/CTNNB1 signaling induces a competing cell proliferation and epidermal differentiation response in the mouse mammary epithelium
L. Mourao, A. L. Zeeman, K. E. Wiese, A. Bongaarts, L. L. Oudejans, I. Mora Martinez, Y. B. C. van de Grift, J. Jonkers, R. van Amerongen
This study investigates the effects of hyperactive WNT/CTNNB1 signaling in mouse mammary epithelium, showing it induces competing proliferation and differentiation responses depending on signaling levels.
bioRxiv · Jun 22, 2021 · PreprintCancer Biology