In vivo reprogramming of murine host immune response genes following Leishmania major infection.
G. Venugopal, J. T. Bird, C. L. Washam, H. Roys, A. Bowlin, S. D. Byrum, T. Weinkopff
This study uses bulk and single-cell RNA sequencing to analyze gene expression changes in mice infected with Leishmania major, identifying upregulated immune pathways and downregulated ribosomal pathways, as well as a novel role for EIF2 signaling.
bioRxiv · Oct 5, 2021 · PreprintImmunology