Author

S. D. Byrum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

C. L. Washam· 2 shared A. Basnakian· 1 shared A. Bowlin· 1 shared A. C. L. Bostian· 1 shared A. Gies· 1 shared A. Graham· 1 shared A. J. Tackett· 1 shared A. Ketkar· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

C. L. Washam

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In vivo Safety and Immunoactivity of Oncolytic Jurona Virus in Hepatocellular Carcinoma: A Comprehensive Proteogenomic Analysis

Y. Zhang, M. Tesfay, K. U. Ferdous, M. Taylor, M. N. Gabere, C. C. Simoes, C. Dumbauld, O. Barro, A. Graham, C. L. Washam, D. Alkam, A. Gies, J. C. Chamcheu, S. D. Byrum, S. R. Post, , B. M. Nagalo

This study evaluates the in vivo safety and immunoactivity of Jurona virus in hepatocellular carcinoma using proteogenomic analysis, showing tumor regression and enhanced immune responses.

bioRxiv · Sep 9, 2022 · PreprintImmunology

p66Shc is an apoptotic rheostat whose targeted ROS inhibition improves MI outcomes

L. Haslem, J. M. Hays, H. Schmitz, S. Matsuzaki, V. Sjoelund, S. D. Byrum, K. M. A. Humphries, J. K. Frazer, B. Demeler, D. M. Benbrook, R. M. Tierney, K. D. Duggan, F. A. Hays

This study identifies p66Shc as a stress-dependent apoptotic rheostat and shows that reducing its pro-apoptotic ROS production improves myocardial infarction outcomes in zebrafish.

bioRxiv · Apr 14, 2022 · PreprintBiochemistry

In vivo reprogramming of murine host immune response genes following Leishmania major infection.

G. Venugopal, J. T. Bird, C. L. Washam, H. Roys, A. Bowlin, S. D. Byrum, T. Weinkopff

This study uses bulk and single-cell RNA sequencing to analyze gene expression changes in mice infected with Leishmania major, identifying upregulated immune pathways and downregulated ribosomal pathways, as well as a novel role for EIF2 signaling.

bioRxiv · Oct 5, 2021 · PreprintImmunology

Inhibition of tryptophan-2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells

M. R. Reed, L. Maddukuri, A. Ketkar, S. D. Byrum, M. K. Zafar, A. C. L. Bostian, A. J. Tackett, R. L. Eoff

This study shows that inhibiting TDO in glioma cells impairs DNA repair and increases sensitivity to DNA-damaging agents.

bioRxiv · May 28, 2020Cancer Biology