PathologybioRxivPreprint
Apelin-VEGF-C mRNA delivery as therapeutic for the treatment of secondary lymphedema
A. Lamaa, J. Creff, E. Benuzzi…·B. Garmy-Susini
This study identifies apelin as a therapeutic molecule for secondary lymphedema, showing it enhances lymphatic function through VEGF-C and pathways involving Akt and eNOS, with a novel RNA delivery system for clinical evaluation.