Author

A. C. Abraham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

A. G. Schwartz· 1 shared B. P. Marshall· 1 shared D. C. Viola· 1 shared E. Ganji· 1 shared G. M. Genin· 1 shared I. Kurtaliaj· 1 shared K. G. Burt· 1 shared M. Golman· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBioengineering

A. G. Schwartz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nuclear Factor Kappa B Over-Activation in the Intervertebral Disc Leads to Macrophage Recruitment and Severe Disc Degeneration

K. G. Burt, M. K. M. Kim, D. C. Viola, A. C. Abraham, N. O. Chahine

This study shows that prolonged NF-κB activation in intervertebral discs causes severe degeneration by increasing inflammation, catabolic enzymes, and macrophage recruitment, with some mitigation by inflammatory-resolving macrophages.

bioRxiv · Aug 7, 2023 · PreprintBioengineering

Optogenetic-Induced Muscle Loading Leads to Mechanical Adaptation of the Achilles Tendon Enthesis in Mice

E. Ganji, S. N. Lamia, M. Stepanovich, N. Whyte, A. C. Abraham, M. L. Killian

This study uses optogenetics to induce muscle loading in mice, showing that young mice's Achilles tendon enthesis adapts structurally and molecularly, while adult mice show no such changes.

Science Advances · Jun 23, 2023Peer-reviewedBioengineering

Toughening mechanisms for the attachment of architectured materials: The mechanics of the tendon enthesis

M. Golman, A. C. Abraham, I. Kurtaliaj, B. P. Marshall, Y. J. Hu, A. G. Schwartz, X. E. Guo, V. Birman, P. J. Thurner, G. M. Genin, S. Thomopoulos

The paper identifies toughening mechanisms in the tendon enthesis using a mouse model, revealing architectural adaptations that optimize strength and toughness across scales.

bioRxiv · May 17, 2021Bioengineering