Free diffusion of PI(4,5)P2 in the plasma membrane in the presence of high density effector protein complexes
J. Pacheco, A. C. Cassidy, J. P. Zewe, R. C. Wills, G. R. Hammond
The paper measures PI(4,5)P2 diffusion in the plasma membrane and finds that it diffuses rapidly even in regions with high effector protein density, suggesting free diffusion rather than spatial segregation.
bioRxiv · Jan 7, 2022Cell Biology