Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechanotransduction
M. Moraes de Lima Perini, J. N. Pugh, E. M. Scott, K. Bhula, A. C. Chirgwin, O. N. Reul, N. F. Berbari, J. Li
This study shows that primary cilia in osteoblasts and osteocytes are essential for skeletal development and mechanotransduction, as demonstrated by reduced bone growth and impaired mechanical loading response in knockout mice.
bioRxiv · Dec 15, 2023 · PreprintCell Biology