BiochemistrybioRxiv
Structure of the mini-RNA-guided endonuclease CRISPR-Cas{Phi}3
A. Carabias del Rey, A. Fuglsang, P. Temperini…·G. Montoya
This paper determines the cryoEM structure of CRISPR-Cas{Phi}3, revealing its DNA targeting and cleavage mechanism, and shows how it enables unspecific ssDNA degradation.
DOI 10.1038/s41467-021-24707-3