Author

A. Carlesso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

A. M. Gorman· 1 shared A. Reymer· 1 shared A. Samali· 1 shared C. Chintha· 1 shared J. Horberg· 1 shared L. A. Eriksson· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperBiochemistry

A. M. Gorman

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2 papers

Recent·Most cited

Mechanistic Insights into ASO-RNA Complexation: Advancing Antisense Oligonucleotide Design Strategies.

J. Horberg, A. Carlesso, A. Reymer

This study uses molecular dynamics simulations to show that ASO-mRNA complex stability depends on ASO length, triple base pairs, and hairpin loop accessibility, offering insights for ASO design.

bioRxiv · Apr 18, 2024Biophysics

Structural distortions induced by Kinase Inhibiting RNase Attenuator (KIRA) compounds prevent the formation of face-to-face dimers of Inositol Requiring Enzyme 1α

A. Carlesso, C. Chintha, A. M. Gorman, A. Samali, L. A. Eriksson

This paper investigates how KIRA compounds disrupt IRE1α dimer formation, inhibiting RNase activity and UPR activation through structural and computational analysis.

bioRxiv · Aug 22, 2019Biochemistry