Mice with humanized livers reveal the involvement of hepatocyte circadian clocks in rhythmic behavior and physiology
A.-S. Delbes, M. Quinones, C. Gobet, J. Castel, R. G. P. Denis, B. Jeremy, B. D. Weger, E. Challet, A. Charpagne, S. Metairon, J. Piccand, M. Kraus, B. Rohde, J. Bial, E. M. Wilson, , S. H. Luquet
This study uses humanized mouse livers to show that peripheral circadian clocks can influence the central pacemaker, altering rhythmic behavior and physiology.
bioRxiv · Sep 8, 2022 · PreprintPhysiology