Author

A. Ciardiello

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. J. Thiele· 1 shared H. Lei· 1 shared J. F. Shern· 1 shared J. J. Hong· 1 shared M. Xu· 1 shared X. Zhang· 1 shared Z. Liu· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

C. J. Thiele

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1 paper

Recent·Most cited

MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes

Z. Liu, X. Zhang, M. Xu, J. J. Hong, A. Ciardiello, H. Lei, J. F. Shern, C. J. Thiele

This study shows MYCN drives oncogenesis by cooperating with WDR5 to activate MYC targets and G9a to repress differentiation genes, and targeting both synergistically inhibits neuroblastoma growth.

bioRxiv · Jul 11, 2023 · PreprintCancer Biology