Author

J. J. Hong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ciardiello· 1 shared A. Soragni· 1 shared B. Tofig· 1 shared B.-S. Koo· 1 shared C. J. Thiele· 1 shared D. Elashoff· 1 shared H. Jang· 1 shared H. Lei· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Ciardiello

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes

Z. Liu, X. Zhang, M. Xu, J. J. Hong, A. Ciardiello, H. Lei, J. F. Shern, C. J. Thiele

This study shows MYCN drives oncogenesis by cooperating with WDR5 to activate MYC targets and G9a to repress differentiation genes, and targeting both synergistically inhibits neuroblastoma growth.

bioRxiv · Jul 11, 2023 · PreprintCancer Biology

Soluble Spike DNA vaccine provides long-term protective immunity against SAR-CoV-2 in mice and nonhuman primates

Y. B. Seo, Y. S. Suh, J. I. Ryu, H. Jang, H. Oh, B.-S. Koo, S.-H. Seo, J. J. Hong, M. Song, S.-J. Kim, Y. C. Sung

This study develops a DNA vaccine against SARS-CoV-2, GX-19, showing protective immunity in mice and nonhuman primates with durable antibody and T cell responses.

bioRxiv · Oct 9, 2020Immunology

A simple high-throughput approach identifies actionable drug responses in patient-derived tumor organoids

N. Phan, J. J. Hong, B. Tofig, M. Mapua, D. Elashoff, N. A. Moatamed, J. Huang, S. Memarzadeh, R. Damoiseaux, A. Soragni

This paper introduces a high-throughput method for drug screening using tumor organoids and identifies effective drugs for ovarian cancer within a week of surgery.

bioRxiv · Aug 13, 2018Cancer Biology