Antibiotic use in early life subsequently impairs MAIT cell-mediated immunity
A. L. Sobel, J. Melamed, D. Haas, G. LeBlanc, A. Cirone, M. G. Constantinides
This study shows that early-life antibiotic use reduces MAIT cell abundance, impairing immunity to pneumonia, but this effect can be reversed by reintroducing riboflavin-synthesizing commensals.
bioRxiv · May 10, 2024 · PreprintImmunology