Author

J. Melamed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Cirone· 1 shared A. L. Sobel· 1 shared A. N. Goga· 1 shared A. Venook· 1 shared B. G. H. Guthrie· 1 shared C. Atreya· 1 shared D. Gempis· 1 shared D. Haas· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Cirone

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Antibiotic use in early life subsequently impairs MAIT cell-mediated immunity

A. L. Sobel, J. Melamed, D. Haas, G. LeBlanc, A. Cirone, M. G. Constantinides

This study shows that early-life antibiotic use reduces MAIT cell abundance, impairing immunity to pneumonia, but this effect can be reversed by reintroducing riboflavin-synthesizing commensals.

bioRxiv · May 10, 2024 · PreprintImmunology

A conserved enzyme found in diverse human gut bacteria interferes with anticancer drug efficacy

P. Spanogiannopoulos, T. S. Kyaw, B. G. H. Guthrie, P. H. Bradley, J. V. Lee, J. Melamed, Y. N. A. Malig, K. N. Lam, D. Gempis, M. Sandy, W. Kidder, E. L. van Blarigan, C. Atreya, A. Venook, R. R. Gerona, , P. Turnbaugh

The paper shows that a conserved enzyme in gut bacteria inactivates anticancer drugs, reducing their efficacy in mice and highlighting microbial contributions to drug metabolism.

bioRxiv · May 2, 2022 · PreprintMicrobiology