Molten globule driven and self-downmodulated phase separation of a viral factory scaffold
G. de Prat Gay, M. Salgueiro, G. Camporeale, A. Visentin, M. Aran, L. Pellizza, S. A. Esperante, A. Corbat, H. Grecco, B. Sousa, R. Esperon, S. Borkosky
The paper shows that the viral protein P undergoes phase separation driven by a molten globule domain and self-downmodulation, forming viral factories through nucleation-condensation with nucleoprotein N.
bioRxiv · Jan 27, 2023Biophysics