Author

A. D. Gnann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

D. P. Dowling· 2 shared A. Veraksa· 1 shared B. M. Castellano· 1 shared C. Barthelemy· 1 shared D. Frueh· 1 shared E. J. Brignole· 1 shared G. Jimenez· 1 shared J. J. M. Liew· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

D. P. Dowling

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Author profile →

2 papers

Recent·Most cited

Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua

J. Webb, A. D. Gnann, J. J. M. Liew, M. Patterson, S. Paul, M. Fores, G. Jimenez, A. Veraksa, D. P. Dowling

This study determines the crystal structure of the CIC HMG-box and C1 domains bound to DNA, revealing their cooperative role in DNA recognition and how mutations disrupt this mechanism.

bioRxiv · Mar 28, 2022Biochemistry

Studies of a siderophore-producing cyclization domain: A refined proposal of substrate binding

A. D. Gnann, Y. Xia, J. Soule, C. Barthelemy, J. S. Mawani, S. Nzikoba Musoke, B. M. Castellano, E. J. Brignole, D. Frueh, D. P. Dowling

This study reports the crystal structure of a Cy domain from Yersinia pestis and explores its interactions with carrier proteins and small-molecule fragments to inform antibiotic design.

bioRxiv · Mar 18, 2022Biochemistry