Author

J. Soule

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. D. Gnann· 1 shared B. M. Castellano· 1 shared B. Mahoney· 1 shared C. Barthelemy· 1 shared C. Taffoni· 1 shared D. Frueh· 1 shared D. P. Dowling· 1 shared E. J. Brignole· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBiochemistry

A. D. Gnann

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Author profile →

3 papers

Recent·Most cited

Studies of a siderophore-producing cyclization domain: A refined proposal of substrate binding

A. D. Gnann, Y. Xia, J. Soule, C. Barthelemy, J. S. Mawani, S. Nzikoba Musoke, B. M. Castellano, E. J. Brignole, D. Frueh, D. P. Dowling

This study reports the crystal structure of a Cy domain from Yersinia pestis and explores its interactions with carrier proteins and small-molecule fragments to inform antibiotic design.

bioRxiv · Mar 18, 2022Biochemistry

Directed inter-domain motions enable the IsdH Staphylococcus aureus receptor to rapidly extract heme from human hemoglobin

J. Clayton, K. Ellis-Guardiola, B. Mahoney, J. Soule, R. T. Clubb, J. Wereszczynski

This study shows directed inter-domain motions in the IsdH receptor enable efficient heme extraction from human hemoglobin by distorting the heme pocket.

bioRxiv · Dec 28, 2021Biophysics

Evolutionary plasticity in the innate immune function of Akirin

J. Polanowska, J.-X. Chen, J. Soule, S. Omi, J. Belougne, C. Taffoni, N. Pujol, M. Selbach, O. Zugasti, J. J. Ewbank

This study identifies conserved and divergent roles of Akirin in innate immune gene regulation across species, revealing lineage-specific adaptations in its functional partners.

bioRxiv · Dec 6, 2017Immunology