TRPV2 interaction with small molecules and lipids revealed by cryo-EM
A. D. Protopopova, R. A. Pumroy, J. de la Roche, F. M. Haug, B. B. Sousa, P. N. Gallo, G. J. L. Bernardes, A. Leffler, V. Moiseenkova-Bell
This study reveals TRPV2 structures bound to small molecules and lipids using cryo-EM, identifying new binding sites and mechanisms of channel gating.
bioRxiv · Aug 10, 2020 · PreprintBiophysics