Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors
A. Schietinger, G. Espinosa-Carrasco, A. Dave, A. Scrivo, H.-S. Lee, B. M. Burt, P. Zumbo, D. Betel, M. Hellmann
This study identifies intratumoral CD4 T cell::CD8 T cell::APC triads as essential for effective adoptive T cell therapy and anti-tumor immunity in both preclinical models and human lung cancer patients.
bioRxiv · Jul 3, 2023 · PreprintImmunology