Author

H.-S. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Plant Biology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:Arabidopsis· 2 Research Focus:cell signaling & trafficking· 2 Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2

Frequent Co-Authors

J.-S. Lee· 2 shared S. Choi· 2 shared S. Kim· 2 shared A. D. Assefa· 1 shared A. Dave· 1 shared A. Hwang· 1 shared A. Schietinger· 1 shared A. Scrivo· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

J.-S. Lee

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Highly effective gene inactivation in tetraploid Xenopus laevis with low-temperature-active engineered Cas12a

S. Yun, S. Kim, J. Hong, S. Shin, J. Choi, J.-S. Shin, S. Choi, H.-S. Lee, S. W. Cho, T. J. Park, T. Kwon

This study evaluates engineered Cas12a variants for gene inactivation in Xenopus laevis, finding that Cas12a-Ultra achieves high efficiency at low temperatures.

bioRxiv · Jul 30, 2023 · PreprintBioengineering

Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors

A. Schietinger, G. Espinosa-Carrasco, A. Dave, A. Scrivo, H.-S. Lee, B. M. Burt, P. Zumbo, D. Betel, M. Hellmann

This study identifies intratumoral CD4 T cell::CD8 T cell::APC triads as essential for effective adoptive T cell therapy and anti-tumor immunity in both preclinical models and human lung cancer patients.

bioRxiv · Jul 3, 2023 · PreprintImmunology

MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

Y.-J. Park, N. Dodantenna, T.-H. Kim, H.-S. Lee, Y.-S. Yoo, E.-S. Lee, J.-H. Lee, M.-H. Kwon, H. C. Kang, J.-S. Lee, H. Cho

This study identifies MARCH5-dependent NLRP3 ubiquitination as essential for NEK7 mitochondrial docking during inflammasome assembly.

bioRxiv · Jan 12, 2023 · PreprintImmunology

Three consecutive glycolysis enzymes are involved in autophagic flux regulation through monitoring nutrient availability

D.-H. Lee, I. Choi, S. J. Park, S. Kim, M.-S. Choi, H.-S. Lee, H.-S. Pai

This study identifies three glycolysis enzymes (TPI, GAPC, PGK) that negatively regulate autophagy by monitoring nutrient availability through their interaction with ATG101.

bioRxiv · Jul 12, 2022 · PreprintPlant Biology

Inhibition of CDK4/6 Overcomes Primary Resistance to PD-1 Blockade in Malignant Mesothelioma

H.-J. Jang, C. Y. Truong, E. M. Lo, H. M. Holmes, D. Ramos, M. Ramineni, J.-S. Lee, D. Y. Wang, M. Pietropaolo, R. T. Ripley, B. Burt, H.-S. Lee

This study identifies CDK4/6 as a therapeutic target to overcome primary resistance to PD-1 blockade in malignant mesothelioma by analyzing genomic and immunogenomic data.

bioRxiv · Mar 4, 2021Immunology

RGI-GOLVEN signalling promotes FLS2 abundance to regulate plant immunity

M. Stegmann, P. Zecua-Ramirez, C. Ludwig, H.-S. Lee, B. Peterson, Z. L. Nimchuk, Y. Belkhadir, R. Hueckelhoven

This study identifies GLV2 peptides as phytocytokines in Arabidopsis that enhance plant immunity by increasing FLS2 abundance through RGI receptor signaling.

bioRxiv · Jan 29, 2021 · PreprintPlant Biology

Determination of glucosinolate contents in Brassica germplasm collections and inter- & intra-leaves distribution pattern using UPLC-MS/MS Multiple Reaction Monitoring scan mode

A. D. Assefa, S. Choi, J.-E. Lee, J.-S. Sung, O.-S. Hur, N.-Y. Ro, H.-S. Lee, J. Noh, A. Hwang, H.-C. Ko, Y.-J. Chung, J. H. Rhee

The paper quantifies glucosinolate (GSL) content in Brassica germplasm and examines inter- and intra-leaf distribution patterns using UPLC-MS/MS, identifying variations and potential applications in breeding.

bioRxiv · Mar 6, 2019 · PreprintBiochemistry