Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency
A. Sanchez, A. de Vivo, P. Tonzi, J. Kim, T. Huang, Y. Kee
This study shows that BMI1 and RNF2 suppress transcription-replication conflicts and CFS instability by regulating RNA Pol II elongation and fork protection.
bioRxiv · Nov 18, 2019Cell Biology