Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide
T. C. Michaels, A. Saric, S. Curk, K. Bernfur, P. Arosio, G. Meisl, A. Dear, S. Cohen, M. Vendruscolo, C. M. Dobson, S. Linse, T. P. Knowles
This study investigates the dynamics of Aβ42 oligomers during amyloid fibril formation, revealing that most oligomers dissociate into monomers rather than forming fibrils.
Nature Chemistry · Apr 13, 2020Peer-reviewedBiophysics