Author

A. Di Cristofano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. J. Sugarman· 1 shared A. Shabro· 1 shared C. Michael· 1 shared L. D. Huynh· 1 shared S. de Oliveira· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperCancer Biology

A. J. Sugarman

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2 papers

Recent·Most cited

A zebrafish xenotransplant model of anaplastic thyroid cancer to study the tumor microenvironment and innate immune cell interactions in vivo.

C. Michael, A. Di Cristofano, S. de Oliveira

bioRxiv · May 29, 2023 · PreprintCancer Biology

Anaplastic Thyroid Cancer Cells Upregulate Mitochondrial One-Carbon Metabolism To Meet Purine Demand, Eliciting A Critical Targetable Vulnerability

A. J. Sugarman, L. D. Huynh, A. Shabro, A. Di Cristofano

This study identifies upregulated mitochondrial one-carbon metabolism in anaplastic thyroid cancer as a targetable vulnerability, showing that inhibiting SHMT2 reduces proliferation and tumor growth.

bioRxiv · Apr 30, 2023Cancer Biology