Author

A. E. Fernandez-Montalvan

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Chaikuad· 1 shared C. Heroven· 1 shared F. Wolfreys· 1 shared G. K. Ganotra· 1 shared P. E. Brennan· 1 shared R. C. Wade· 1 shared S. Knapp· 1 shared V. Georgi· 1 shared

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2018-2018 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

A. Chaikuad

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1 paper

Recent·Most cited

BiophysicsbioRxivJan 29, 2018

Halogen-aromatic π-interactions modulate inhibitor residence time

C. Heroven, V. Georgi, G. K. Ganotra…·S. Knapp

The paper shows that halogen-aromatic π-interactions increase inhibitor residence time in kinase-inhibitor complexes, providing a strategy to improve drug efficacy and selectivity.

DOI 10.1002/anie.201801666

statistical modelexperimental assay

𝕏 PostBluesky