Author

A. E. Goodspeed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. C. Costello· 2 shared A. D. Durbin· 1 shared E. K. Bordeaux· 1 shared E. P. Danis· 1 shared H. L. Ford· 1 shared J. C. Black· 1 shared J. C. Talbot· 1 shared J. L. Sottnik· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

J. C. Costello

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Author profile →

2 papers

Recent·Most cited

SIX1 Reprograms Myogenic Transcription Factors to Maintain the Rhabdomyosarcoma undifferentiated state

J. Y. Hsu, E. P. Danis, S. Nance, J. O'Brien, V. M. Wessells, A. E. Goodspeed, J. C. Talbot, S. L. Amacher, P. Jedlicka, J. C. Black, J. C. Costello, A. D. Durbin, K. B. Artinger, H. L. Ford

This study shows that SIX1 maintains the undifferentiated state of rhabdomyosarcoma cells by altering MYOD1 activity and enhancer regulation, and a SIX1 loss gene signature predicts RMS progression.

bioRxiv · Apr 25, 2021Cancer Biology

Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast

E. K. Bordeaux, J. L. Sottnik, S. Mehrotra, S. E. Ferrara, A. E. Goodspeed, J. C. Costello, M. J. Sikora

This study identifies MDC1 as a novel ER co-regulator in ILC that promotes ER-driven proliferation and anti-estrogen resistance.

bioRxiv · Dec 16, 2020Cancer Biology