Calcium dependence of both lobes of calmodulin is involved in binding to a cytoplasmic domain of SK channels
D. B. Halling, A. E. Philpo, R. W. Aldrich
The paper investigates the role of calmodulin's N- and C-lobes in SK channel gating, finding that both lobes are required for full activation and that their Ca2+ dependence affects binding to the channel.
eLife · Dec 30, 2022Peer-reviewedBiophysics