Author

R. W. Aldrich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1

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Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. Philpo· 1 shared B. Liebeskind· 1 shared D. B. Halling· 1 shared E. M. Marcotte· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 2 mutual co-author links

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1 shared paperBiophysics

A. E. Philpo

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2 papers

Recent·Most cited

Calcium dependence of both lobes of calmodulin is involved in binding to a cytoplasmic domain of SK channels

D. B. Halling, A. E. Philpo, R. W. Aldrich

The paper investigates the role of calmodulin's N- and C-lobes in SK channel gating, finding that both lobes are required for full activation and that their Ca2+ dependence affects binding to the channel.

eLife · Dec 30, 2022Peer-reviewedBiophysics

Ancestral Reconstruction of Protein Interaction Networks

B. Liebeskind, R. W. Aldrich, E. M. Marcotte

The paper infers ancestral states and evolutionary dynamics of protein-interaction networks using phylogenetic latent variable models and mass spectrometry data.

bioRxiv · Sep 9, 2018Evolutionary Biology