Pharmacology & ToxicologybioRxivPreprint
Apelin inhibits cyst growth and improves kidney function in mice with polycystic kidney disease
Duuamene Nyimanu, Anubhav Chakraborty, Stephen C. Parnell…·A. Ershova Yu.
This study shows that apelin reduces cyst growth and improves kidney function in a mouse model of ADPKD by inhibiting cAMP synthesis and downregulating cyst-related genes.
DOI 10.64898/2026.03.26.714294