Author

Anubhav Chakraborty

University of Kansas Medical CenterORCID 0000-0002-3951-4469Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Darren P. WallaceiD· 2 shared A. Ershova Yu.· 1 shared Aakriti Chaturvedi· 1 shared Alan S.L. YuiD· 1 shared Anil Kumar Ram· 1 shared Christopher J. WardiD· 1 shared Duuamene NyimanuiD· 1 shared Henrietta EhirimiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Darren P. WallaceORCID

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3 papers

Recent·Most cited

Molecular BiologyAmerican Journal of Physiology-Renal PhysiologyPeer-reviewedSep 22, 2026

CRISPR activation of endogenous PKD1 increases polycystin-1 levels and suppresses cellular features of ADPKD

Anubhav Chakraborty, Meekha M. Varghese, Darren P. Wallace…·Alan S.L. Yu

This study uses CRISPR activation to increase PKD1 expression in ADPKD models, reducing cyst formation and improving cellular features.

DOI 10.1152/ajprenal.90084.2026

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Pharmacology & ToxicologybioRxivPreprintMar 30, 2026

Apelin inhibits cyst growth and improves kidney function in mice with polycystic kidney disease

Duuamene Nyimanu, Anubhav Chakraborty, Stephen C. Parnell…·A. Ershova Yu.

This study shows that apelin reduces cyst growth and improves kidney function in a mouse model of ADPKD by inhibiting cAMP synthesis and downregulating cyst-related genes.

DOI 10.64898/2026.03.26.714294

mouseproteomics

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Molecular BiologyDisease Models & MechanismsPeer-reviewedFeb 1, 2025

Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease

Mackenzie M. Thornton, Nicole Sommer, Mercedes B. Mcgonigle…·Madhulika Sharma

This study shows that Notch3 deletion reduces HIV-1 gene expression and systemic inflammation, improving outcomes in HIV-associated chronic kidney disease.

5 citations

mousebulk RNA-seq

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